método para determinar o prognóstico de um paciente que sofre de câncer e composição de agente indutor de atividade de chok(beta)

摘要

The present invention relates to methods for the treatment of cancer based on the induction of the choline kinase beta (hereinafter ChoK²) activity as well as to methods for the design of personalized therapies and for determining the response of an agent capable of inducing choline kinase beta (hereinafter ChoK²) for the treatment of cancer as well as to methods for determining the prognosis of a patient based on the determination of the ChoK² expression levels as well as based on the determination of the relationship between the ChoK² and ChoK± expression levels. Finally, the invention relates to methods for determining the response of a patient who suffers from cancer to ChoK±-inhibiting agents based on the determination of the PEMT and/or ChoKp expression levels.