| 发明名称 | Dry composition of reaction compounds with stabilized polymerase | ||
| 摘要 | The present invention provides methods to obtain dry compositions of reaction compounds that maintain the biological activity of the compounds upon re-solubilization after a certain storage time. Preferably, the dry composition comprises a polymerase, and the dry composition is usable for polymerase chain reaction (PCR) amplification after re-solubilization. | ||
| 申请公布号 | US9163286(B2) | 申请公布日期 | 2015.10.20 |
| 申请号 | US201414169993 | 申请日期 | 2014.01.31 |
| 申请人 | Roche Diagnostics Operations, Inc. | 发明人 | Metzler Thomas;Haslinger Tobias;Peceny Annette;Sobek Harald |
| 分类号 | C12P19/34;C12Q1/68;C12N9/12 | 主分类号 | C12P19/34 |
| 代理机构 | Faegre Baker Daniels LLP | 代理人 | Faegre Baker Daniels LLP |
| 主权项 | 1. A dry composition of reaction compounds comprising primers, nucleotides, a Taq DNA polymerase, a first stabilizing molecule, and an aptamer as a second stabilizing molecule, the dry composition providing polymerase chain reaction (PCR) activity upon re-solubilization after storage at room temperature for at least one week. | ||
| 地址 | Indianapolis IN US | ||