| 摘要 |
FIELD: medicine.SUBSTANCE: present invention relates to use of a compound of formula (I), aggregates and a pharmaceutical composition based thereon. In formula(I) R1 is methyl or ethyl; R2 is R3 or R4; "X" is O or S; and "A" is C3-7alkanediyl, if R2 is R3, and C2-7 alkanediyl if R2 is R4, where X and R2 are bonded to different carbon atoms of said alkanediyl and wherein said different carbon atoms are the carbon atoms in the alkanediyl being most spaced apart; R3 is selected from N(C0-3alkyl)C(O)R5, OC(O)R5, C(O)N(C0-3alkyl)R5 and C(O)OR5, R5 is a straight carbon chain comprising 14 to 30 carbon atoms, said carbon chain being saturated or comprising one or more double and/or triple bonds; furthermore, said carbon chain is unsubstituted or substituted with one or more C1-C5 alkyl groups; R4 is a substitute of formula (II): D(CH)(OCHCH)(CH)ER(II), where "D" is bonded to "A" and is selected from N(C0-3alkyl)C(O), OC(O), C(O)N(C0-3alkyl) and C(O)O; "m" and "p" are equal to 0-3; "n" is equal to 1-15; "E" is selected from N(C0-3alkyl)C(O), OC(O), C(O)N(C0-3alkyl) and C(O)O; and R7 is R5, in the form of an acid in non-charged protonated form, a pharmaceutically acceptable addition salt or solvate, in the form of a stereoisomer or anomeric mixture in which the ?-anomer prevails.EFFECT: treating and preventing eye viral infections.24 cl, 3 dwg, 1 tbl, 3 ex |
