| 摘要 |
<p>(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/175013 A1 (51) International Patent Classification: A61K31/46 (2006.01) A61P11/08 (2006.01) A61M15/00 (2006.01) A61K31/573 (2006.01) A61P11/06 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 12382211.6 61/654,224 61/779,578 PCT/EP2013/060808 24 May 2013 (24.05.2013) English English EP US US 25 May 2012 (25.05.2012) 1 June 2012 (01.06.2012) 13 March 2013 (13.03.2013) (71) Applicant: ALMIRALL, S.A. [ES/ES]; Ronda del Gener al Mitre 151, E-08022 Barcelona (ES). (72) Inventors: LAMARCA CASADO, Rosa; C/ Laurea Miro 408-410, Sant Feliu de Llobregat, E-08980 Barcelona (ES). DE MIQUEL SERRA, Gonzalo; C/ Laurea Miro 408-410, Sant Feliu de Llobregat, E-08980 Barcelona (ES). (74) Agent: SRINIVASAN, Ravi Chandran; J A Kemp & Co., 14 South Square, Gray's Inn, London Greater London WC1R 5JJ (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published:—with international search report (Art. 21(3)) i-H o i> i-H o CJ (54) Title: NOVEL DOSAGE AND FORMULATION (57) Abstract: A pharmaceutical composition for inhalation comprising aclidinium in the form of a dry powder of a pharmaceutic - ally acceptable salt in admixture with pharmaceutically acceptable a dry powder carrier, providing a delivered dose of aclidinium equivalent to about 322 micrograms aclidinium free base.</p> |
