METHOD OF TREATING DEPRESSION

摘要

Methods are disclosed herein for treating depression in the subject. A method includes the use of Botulinum toxin to cause paralysis of a facial muscle, such as the depressor anguli oris, procerus, frontalis, orbicularis oculi, or corrugator supercilii muscle to treat depression in the subject.

主权项

1. A method for treating dysthymia, major depression or a mood disorder in a subject, comprising:
administering a therapeutically effective amount of a composition comprising a botulinum toxin to one or more facial muscle involved in frowning, scowling or a sad appearance; wherein the therapeutically effective amount is an amount sufficient to cause paralysis of the one or more facial muscle; thereby treating dysthymia, major depression or a mood disorder in the subject.