METHODS OF USE FOR PROBIOTICS AND PREBIOTICS

摘要

The present disclosure relates to method(s) for reducing the risk of visceral pain hypersensitivity, modulating the gut-brain axis, or reducing the local inflammatory response in a subject. The method(s) include providing a nutritional composition that includes Lactobacillus rhamnosus GG (LGG), galacto-oligosaccharide(s) (GOS) and polydextrose (PDX) to the subject. The combination of LGG, GOS, and PDX may exhibit additive or synergistic beneficial health effects when consumed. The nutritional compositions herein are suitable for administration to children and infants.

主权项

1. A method for reducing the risk of visceral pain hypersensitivity and reducing the functional abdominal pain and infantile colic in a pediatric subject comprising providing to the pediatric subject a nutritional composition comprising, a carbohydrate source, a protein source, a fat source, from about 1×104 CFU/100 kcal to about 1.5×1010 CFU/100 kcal of Lactobacillus rhamnosus GG, from about 0.1 g/100 kcal to about 0.5 g/100 kcal of polydextrose, and from about 0.1 g/100 kcal to about 1.0 g/100 kcal of galacto-oligosaccharides.