METHODS OF ENHANCING FUNCTIONING OF THE LARGE INTESTINE

摘要

The invention relates to glucagon-related peptides and their use for the prevention or treatment of disorders involving the large intestine. In particular, it has now been demonstrated that GLP-2 and peptidic agonists of GLP-2 can cause proliferation of the tissue of large intestine. Thus, the invention provides methods of proliferating the large intestine in a subject in need thereof. Further, the methods of the invention are useful to treat or prevent inflammatory conditions of the large intestine, including inflammatory bowel diseases.

主权项

1. A method for treating a subject to enhance functioning of the large intestine, comprising the step of delivering to the large intestine of the subject a GLP-2 receptor agonist in an amount effective to enhance functioning of the large intestine.