主权项 |
1. A compound having a structure according to the formula:wherein
Ra is a member selected from CN, C(O)NR1R2, C(O)OR3 wherein R3 is a member selected from H and substituted or unsubstituted alkyl, X is a member selected from N, CH and CRb, Rb is a member selected from halogen and substituted or unsubstituted alkyl, C(O)R4, C(O)OR4, OR4, NR4R5, wherein R1, R2, R4 and R5 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl, with the proviso that R1 and R2, together with the atoms to which they are attached, are optionally combined to form a 4- to 8-membered substituted or unsubstituted heterocycloalkyl ring with the proviso that R4 and R5, together with the atoms to which they are attached, are optionally combined to form a 4- to 8-membered substituted or unsubstituted heterocycloalkyl ring,and salts thereof. |