POLYPEPTIDE COMPOSITIONS WITH TYPE VII COLLAGEN FIBRONECTIN TYPE III- LIKE REPEATS AND TREATMENT METHODS FOR WOUND CLOSURE AND HEALING

摘要

Disclosed are compositions arid methods for accelerating wound closure and preventing inhibiting or reducing scarring or fibrosis. The methods of the present invention include administering to a person in need thereof an effective amount of a pharmaceutical composition comprising collagen 7 and/or one: or snore functional fragments or variants thereof. The functional fragments generally comprise at last one of the nine Fibronectin Type Ill-like Region of the NC1 region of collagen 7.