| 摘要 |
Title compds. (I; R1, R2 = H, C1-4 alkyl; R3 = H, C1-4 alkyl, phenyl, benzyl, C3-5 alkanoyloxymethyl; X = halogen, CF3, C1-6 alkyl etc.; A = single bond or C1-3 alkylene), with diuretic and saluretic action are prepd. by treating 5-halo- genosulfonyl benzoic acid derivs.(II; Hal = halogen) with III. If, necessary a process such as adding hydrogen to double bond, inducing double bond, esterifying carboxylic acid, hydrolysing carboxylic ester, separating protected group and liberating hydroxyl, amino or mercapto group and treating carboxylic acid with base or acid can be accepted.
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