SEAWEED EXTRACTS, UNSATURATED FATTY ACIDS, AND METHODS OF TREATMENT

摘要

The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.

主权项

1. An extract from the seaweed Ulva lactuca isolated by:
a). exposing said seaweed to a solvent or solvent combination; b). filtering the material/mixture from step a); c). removing the solvent or solvent combination from b) to afford a residue; d). partitioning said residue between an organic solvent or organic solvent combination and water; e). separating the organic phase and the water phase from d); f). removing the organic solvent or organic solvent combination from the said organic phase from e); g). purifying the material/mixture from f) using chromatography, collecting fractions.