| 发明名称 |
DIAGNOSIS AND TREATMENT OF CANCER |
| 摘要 |
Provided herein are methods for diagnosing cancer by determining the level of expression of SETDB1 in a biological sample. Also provided herein are methods for treating cancer by administering an inhibitor of SETDB1 to a subject in need thereof. |
| 申请公布号 |
US2015293099(A1) |
申请公布日期 |
2015.10.15 |
| 申请号 |
US201514701810 |
申请日期 |
2015.05.01 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
Zon Leonard I.;Ceol Craig;Houvras Yariv J. |
| 分类号 |
G01N33/574;C12Q1/68;A61K39/395 |
主分类号 |
G01N33/574 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for facilitating the diagnosis of cancer in a subject, the method comprising: measuring the level of SETDB1 in a biological sample obtained from a subject, wherein an increase in the SETDB 1 level in the sample compared to a reference is indicative of cancer in the subject. |
| 地址 |
Boston MA US |
