发明名称 |
TREATMENT OF CANCER BY TARGETING QUIESCENT CANCER CELLS |
摘要 |
A method for treating a subject suffering from a neoplasm, comprising determining the expression level of a DYRK1 selected from DYRK1A or DYRK1B within a cell population in a sample of neoplastic cells and determining the quiescent state of these cells, and if the DYRK1 is expressed in the sample then administering an effective amount of a modulator of DYRK1 activity, either alone or as a part of a combination therapy. |
申请公布号 |
US2015292032(A1) |
申请公布日期 |
2015.10.15 |
申请号 |
US201314679048 |
申请日期 |
2013.10.10 |
申请人 |
FELICITEX THERAPEUTICS, INC. |
发明人 |
Vilenchik Maria;Frid Michael;Gankin Yuri |
分类号 |
C12Q1/68;G01N33/574;A61K31/519;A61K31/4192;C07D249/18;A61K38/08;C07K7/06;C07D471/04;C07D473/16;A61N5/10;A61K31/52 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Newton MA US |