发明名称 |
MERTK-SPECIFIC PYRIMIDINE COMPOUNDS |
摘要 |
The present invention includes pyrimidine compounds that selectively inhibit Mer tyrosine kinase (MerTK) activity and/or Tyro3 tyrosine kinase activity, and use of these pyrimidine compounds as anti-cancer agents, immunostimulatory and immunomodulatory agents, anti-platelet agents, anti-infective agents, and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms. |
申请公布号 |
WO2015157115(A1) |
申请公布日期 |
2015.10.15 |
申请号 |
WO2015US24301 |
申请日期 |
2015.04.03 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
WANG, XIAODONG;ZHANG, DEHUI;FRYE, STEPHEN;KIREEV, DMITRI |
分类号 |
C07D487/04;C07D471/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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