VACCINE COMPOSITION COMPRISING 5'-END CAP MODIFIED RNA

摘要

PROBLEM TO BE SOLVED: To provide a recombinant vaccine for inducing an immune response against a specific antigen, for preventing and treating infectious or cancerous diseases.SOLUTION: The present invention relates to the use of RNA modified with 5'-end cap analogs. The present invention also relates to a vaccine composition comprising the stabilized RNA, immature antigen presenting cells comprising the stabilized RNA, and methods for stimulating and/or activating immune effector cells and for inducing an immune response in an individual using the stabilized RNA.