发明名称 |
METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG |
摘要 |
Methods of quantifying a N2-carboxyethyl-2′-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of disorders, including diabetes and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels occurs using liquid chromatography electrospray ionization tandem mass spectrometry. |
申请公布号 |
US2015290156(A1) |
申请公布日期 |
2015.10.15 |
申请号 |
US201414536299 |
申请日期 |
2014.11.07 |
申请人 |
CITY OF HOPE |
发明人 |
RAHBAR Samuel;SYNOLD Timothy W.;TERMINI John |
分类号 |
A61K31/195;G01N30/72;A61N5/10;A61K45/06 |
主分类号 |
A61K31/195 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
DUARTE CA US |