| 发明名称 |
O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES |
| 摘要 |
The present invention relates to an improved process for O-demethylating methoxy substituted morphinan-6-one derivatives using AlCl3 as a demethylating agent in a reaction-inert solvent having a water content ranging from 0.1 %wt to 0.8 %wt.10 |
| 申请公布号 |
CA2945035(A1) |
申请公布日期 |
2015.10.15 |
| 申请号 |
CA20152945035 |
申请日期 |
2015.04.07 |
| 申请人 |
CILAG AG |
发明人 |
WEIGL, ULRICH GEORG;STAMPFLI, DOMINIK STEFAN;MAURER, NELLI |
| 分类号 |
C07D489/08 |
主分类号 |
C07D489/08 |
| 代理机构 |
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