发明名称 |
COMPOUNDS AND METHODS FOR DETERMINATION OF FKBP-BINDING IMMUNOSUPPRESSANT DRUGS |
摘要 |
Compositions are disclosed for releasing an FKBP-binding immunosuppressant drug from endogenous binding substances in a sample suspected of containing the FKBP-binding immunosuppressant drug. The compositions include sirolimus derivatives that are modified with a bulky organic radical in the triene portion of the sirolimus molecule. The compositions may be employed in conjunction with assays for an FKBP-binding immunosuppressant drug in a sample suspected of containing the drug. |
申请公布号 |
EP2928872(A1) |
申请公布日期 |
2015.10.14 |
申请号 |
EP20130860740 |
申请日期 |
2013.12.03 |
申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS INC. |
发明人 |
ZHENG, YI FENG;WEI, TIE Q. |
分类号 |
C07D237/04 |
主分类号 |
C07D237/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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