METHOD FOR PRODUCING [3-[(6-CHLOR-3-PRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE

摘要

Process for preparing [3-[(6-chloro-3-pyridinyl)methyl]-2-thiazolidinylidene]cyanamide, comprising the following steps: (i) reaction of dimethyl N-cyanocarbonimidodithiocarbonate and 2-aminoethanethiol or a salt thereof in the presence of a base; (ii) reaction of the reaction mixture with 5-chloromethyl-2-chloropyridine, which does not need any purification of the cyanimino-1,3-thiazolidine intermediate.