Cross-linked peptides related to human p53 and bind to HMD2 or a family member of HDM2 useful for promoting apoptosis, e.g., in the treatment of and identifying therapeutic agents that binding to HMD2 or a family member of HDM2.
申请公布号
EP2118123(B1)
申请公布日期
2015.10.14
申请号
EP20080728649
申请日期
2008.01.31
申请人
DANA-FARBER CANCER INSTITUTE, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE
发明人
BERNAL, FEDERICO;WALENSKY, LOREN D.;VERDINE, GREGORY L.;KORSMEYER, STANLEY
