Polar thermoplastic ophthalmic lens molds, ophthalmic lenses molded therein, and related methods

摘要

Ophthalmic lens molds made from one or more thermoplastic polymers with average polarities from about 1% to about 7%, ophthalmic lenses including silicone hydrogel contact lenses molded using these less polar thermoplastic polymers, and related methods are described. When the molds are used to cast mold silicone hydrogel contact lenses, the resulting polymerized lens bodies have ophthalmically acceptably wettable surfaces.

主权项

1. A method of manufacturing a silicone hydrogel contact lens body, comprising:
providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to mold a posterior surface of a contact lens, the molding surface of at least one of the first mold member and the second mold member comprising at least one polar thermoplastic polymer with an average polarity of from 1% to 7%, the first mold member and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold assembly; placing a polymerizable composition comprising a) at least one silicone monomer, silicone macromer, silicone prepolymer, or combination thereof, and b) at least one hydrophilic monomer in the first mold member; assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body; wherein the lens body has ophthalmically acceptably wettable anterior and posterior surfaces without application of a surface treatment to the lens body, or without the presence of an interpenetrating network (IPN) of a polymeric wetting agent in the lens body.