Analyte sensors comprising high-boiling point solvents

摘要

Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

主权项

1. A method for monitoring a level of an analyte using an analyte monitoring system, the method comprising:
inserting at least a portion of an analyte sensor of an analyte sensor control unit into skin of a patient, wherein the analyte sensor comprises:
a working electrode;a counter electrode; anda sensing layer disposed proximate to the working electrode, wherein the sensing layer comprises polymer, enzyme, and a high-boiling point solvent at a concentration of 1% to 5% (w/v) of the total formulation of the sensing layer, collecting data, using the analyte sensor control unit, regarding a level of an analyte from signals generated by the analyte sensor; and transmitting the collected data from the analyte sensor control unit to a receiver unit.