发明名称 |
Isoxazolidine derivatives |
摘要 |
Glucocorticosteroids that are derivatives of isoxazolidine are useful as anti-inflammatory and antiallergic compounds of the glucocorticosteroid series. |
申请公布号 |
US9155747(B2) |
申请公布日期 |
2015.10.13 |
申请号 |
US201313964298 |
申请日期 |
2013.08.12 |
申请人 |
Chiesi Farmaceutici S.p.A. |
发明人 |
Ghidini Eleonora |
分类号 |
A61K31/58;A61M11/00;A61M15/00;A61K45/06;C07J71/00 |
主分类号 |
A61K31/58 |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A compound of formula (I): wherein R1 is linear or branched (C1-C16)alkyl, linear or branched (C2-C18)alkenyl, —OR6, aryl, aryl(C1-C16)alkyl, —SR6, —N(R4)(R5), (C3-C8)cycloalkyl, (C3-C8)heterocycloalkyl, or heteroaryl, wherein optionally one or more hydrogen atoms are replaced by (C1-C6)alkyl, and wherein R4 and R5 are independently H or linear or branched (C1-C6)alkyl, and R6 is linear or branched (C1-C16)alkyl; R2 is aryl optionally substituted by one or more halogen atoms, or a pharmaceutically acceptable salt thereof. |
地址 |
Parma IT |