发明名称 Chemical compounds
摘要 There is provided pyrimidinyl compounds of Formula (I),; wherein: R2 is; or pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
申请公布号 US9155742(B2) 申请公布日期 2015.10.13
申请号 US201514631961 申请日期 2015.02.26
申请人 AstraZeneca AB 发明人 Foote Kevin Michael;Nissink Johannes Wilhelmus Maria;Turner Paul
分类号 A61K31/506;C07D403/14;A61K31/5377 主分类号 A61K31/506
代理机构 AstraZeneca 代理人 AstraZeneca ;Kopp Daniel A.
主权项 1. A method for treating lung cancer which comprises administering to a patient in need thereof a therapeutically effective amount of a compound of formula (I):wherein: R1 is 3-methylmorpholin-4-yl; R2 is R2C is hydrogen; R2D is hydrogen; R3 is methyl; R4 and R5 together with the atom to which they are attached form Ring A; Ring A is a cyclopropyl ring; and R6 is hydrogen;or a pharmaceutically acceptable salt thereof.
地址 Sodertalje SE