发明名称 |
Chemical compounds |
摘要 |
There is provided pyrimidinyl compounds of Formula (I),;
wherein:
R2 is;
or pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. |
申请公布号 |
US9155742(B2) |
申请公布日期 |
2015.10.13 |
申请号 |
US201514631961 |
申请日期 |
2015.02.26 |
申请人 |
AstraZeneca AB |
发明人 |
Foote Kevin Michael;Nissink Johannes Wilhelmus Maria;Turner Paul |
分类号 |
A61K31/506;C07D403/14;A61K31/5377 |
主分类号 |
A61K31/506 |
代理机构 |
AstraZeneca |
代理人 |
AstraZeneca ;Kopp Daniel A. |
主权项 |
1. A method for treating lung cancer which comprises administering to a patient in need thereof a therapeutically effective amount of a compound of formula (I):wherein:
R1 is 3-methylmorpholin-4-yl; R2 is R2C is hydrogen; R2D is hydrogen; R3 is methyl; R4 and R5 together with the atom to which they are attached form Ring A; Ring A is a cyclopropyl ring; and R6 is hydrogen;or a pharmaceutically acceptable salt thereof. |
地址 |
Sodertalje SE |