| 发明名称 | Polycyclic heteroaryl substituted triazoles useful as axl inhibitors | ||
| 摘要 | Polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed. | ||
| 申请公布号 | US9156820(B2) | 申请公布日期 | 2015.10.13 |
| 申请号 | US201414261094 | 申请日期 | 2014.04.24 |
| 申请人 | Rigel Pharmaceuticals, Inc. | 发明人 | Goff Dane;Zhang Jing;Singh Rajinder;Holland Sacha;Yu Jiaxin;Heckrodt Thilo J.;Ding Pingyu;Litvak Joane |
| 分类号 | A61K31/502;C07D237/26;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D417/04;C07D417/14;C07D451/04;C07D471/04;C07D487/04;C07D487/10;C07D491/04;C07D491/20;C07D495/04;C07D519/00 | 主分类号 | A61K31/502 |
| 代理机构 | Seed IP Law Group PLLC | 代理人 | Seed IP Law Group PLLC ;Young Travis |
| 主权项 | 1. A compound having the structure:as a free base, a pharmaceutically acceptable salt thereof or an N-oxide thereof. | ||
| 地址 | South San Francisco CA US | ||