Method and apparatus for improving cardiac efficiency based on myocardial oxygen consumption

摘要

Devices and methods for improving cardiac efficiency involve measuring, patient-internally, an oxygen saturation parameter indicative of oxygen usage of myocardial tissue of the heart. A cardiac electrical therapy is adjusted to cause a change of the measured oxygen saturation parameter, and the adjusted cardiac electrical therapy is selected for delivery based on a changed oxygen saturation parameter indicative of an increase in cardiac efficiency.

主权项

1. A method of improving cardiac efficiency, comprising:
measuring, patient-internally in at least one of a coronary vein and the great cardiac vein of the patient's heart, oxygen saturation indicative of oxygen usage of myocardial tissue of the heart; measuring cardiac stroke volume; calculating a cardiac efficiency parameter based on the measured oxygen saturation and the measured stroke volume; adjusting a cardiac electrical therapy to cause a change of the measured oxygen saturation; calculating a change in the cardiac efficiency parameter resulting from the cardiac electrical therapy adjustment; determining whether the adjustment in the cardiac electrical therapy decreased or increased cardiac efficiency based on the calculated change in the cardiac efficiency parameter; and selecting the adjusted cardiac electrical therapy for delivery if the adjustment of the cardiac electrical therapy was determined to increase cardiac efficiency, wherein at least some of the steps of calculating the cardiac efficiency parameter, calculating the change, determining, and selecting are performed at least in part by circuitry.