发明名称 |
C-3 ALKYL AND ALKENYL MODIFIED BETULINIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF HIV. |
摘要 |
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV: a compound of Formula I; a compound of Formula II; a compound of Formula III: and a compound of Formula IV. These compounds are useful for the treatment of HIV and AIDS. |
申请公布号 |
MX2015010354(A) |
申请公布日期 |
2015.10.09 |
申请号 |
MX20150010354 |
申请日期 |
2014.02.21 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
NICHOLAS A. MEANWELL;YAN CHEN;ZHENG LIU;JIE CHEN;JACOB SWIDORSKI;SING-YUEN SIT;ALICIA REGUEIRO-REN;LI XU;RICHARD A. HARTZ |
分类号 |
C07J63/00;A61K31/56;A61P31/18 |
主分类号 |
C07J63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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