| 摘要 |
PROBLEM TO BE SOLVED: To provide compositions and methods for eliciting an immune response against Porphyromonas gingivalis.SOLUTION: Compositions and methods relate to P. gingivalis polypeptides and fragments and variants thereof, and to corresponding polynucleotides which are useful in diagnosis, prevention and therapy of P. gingivalis infections (e.g., periodontitis). Antibodies against the polypeptides and compositions and methods including these antibodies are also disclosed. The disclosure also describes methods for detection, prevention and treatment of P. gingivalis infections (e.g., periodontitis). |
