发明名称 TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS
摘要 Provided herein are methods, kits, and pharmaceutical compositions that include a PI3 kinase inhibitor for treating cancers or hematologic disorders.
申请公布号 US2015283142(A1) 申请公布日期 2015.10.08
申请号 US201314439965 申请日期 2013.11.01
申请人 INFINITY PHARMACEUTICALS, INC. 发明人 Stern Howard M.;Kutok Jeffery L.
分类号 A61K31/52;A61K31/519;A61K31/704;G01N15/10;A61K31/505;G01N33/574;G01N33/50;C07D473/34;A61K45/06 主分类号 A61K31/52
代理机构 代理人
主权项 1. A method for treating a specific cancer or hematologic malignancy having a high expression level of one or more isoform(s) of phosphoinositide 3-kinase (PI3K) in a subject, comprising administering a PI3K modulator that selectively reduces the activity of said one or more isoform(s) of PI3K over other isoforms of PI3K.
地址 Cambridge MA US