PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASE BY SEPSIS

摘要

The present invention relates to a pharmaceutical composition for preventing and treating inflammatory diseases and, more specifically, a silent information regulator 2 (SIRT2) inhibitor of the present invention can be an effective method for preventing and treating renal inflammatory diseases by septicemia due to alleviating renal inflammation through inhibiting expression of CXCL2 and CCL2, which are inflammation-inducing factors induced by a lipopolysaccharide (LPS), and inhibiting a kidney injury.