| 发明名称 |
COMPOSITIONS FOR MODULATING SOD-1 EXPRESSION |
| 摘要 |
Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS). |
| 申请公布号 |
CA2942394(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
CA20152942394 |
申请日期 |
2015.04.01 |
| 申请人 |
IONIS PHARMACEUTICALS, INC. |
发明人 |
SWAYZE, ERIC E.;COLE, TRACY;KORDASIEWICZ, HOLLY;FREIER, SUSAN M.;CONDON, THOMAS P.;WANCEWICZ, EDWARD;LOCKHART, TRISHA;VICKERS, TIMOTHY;SINGH, PRIYAM |
| 分类号 |
A61K48/00;A61K31/713;A61P25/28;C07H21/02;C07H21/04;C12N15/11;C12Q1/68 |
主分类号 |
A61K48/00 |
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