| 发明名称 |
PYRAZOLOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER |
| 摘要 |
Compounds of Formula I are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof. |
| 申请公布号 |
US2015284392(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
US201314436356 |
申请日期 |
2013.10.16 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
Wang Xiaodong;Liu Jing;Yang Chao;Zhang Weihe;Frye Stephen;Kireev Dmitri |
| 分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of Formula I:wherein:
R1 is phenyl substituted from 1 to 3 times with heterocycloalkylalkyl, which heterocycloalkyl is unsubstituted or substituted from 1 to 3 times with halo or loweralkyl, R2 is —R5R6, where R5 is a covalent bond and R6 is cyclohexyl substituted once with hydroxyl; R3 is —NR7R8, where R7 is H and and R8 is loweralkyl; R4 is H, or a pharmaceutically acceptable salt thereof. |
| 地址 |
Chapel Hill NC US |
