发明名称 Glyco-Engineered Antibodies
摘要 The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.
申请公布号 US2015284461(A1) 申请公布日期 2015.10.08
申请号 US201514724514 申请日期 2015.05.28
申请人 GREENOVATION BIOTECH GMBH 发明人 Schuster Manfred;Kircheis Ralf;Nechansky Andreas;Jost Wolfgang;Gorr Gilbert
分类号 C07K16/28 主分类号 C07K16/28
代理机构 代理人
主权项
地址 Freiburg DE