| 发明名称 |
STRING GRAPH ASSEMBLY FOR POLYPLOID GENOMES |
| 摘要 |
Exemplary embodiments provide methods and systems for string graph assembly of polyploid genomes. Aspects of the exemplary embodiment include receiving a string graph generated from sequence reads of at least 0.5 kb in length; identifying unitigs in the string graph and generating a unitig graph; and identifying string bundles in the unitig graph by: determining a primary contig from each of the string bundles; and determining associated contigs that contain structural variations compared to the primary contig. |
| 申请公布号 |
US2015286775(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
US201514743713 |
申请日期 |
2015.06.18 |
| 申请人 |
Pacific Biosciences of California, Inc. |
发明人 |
Chin Chen-Shan |
| 分类号 |
G06F19/22 |
主分类号 |
G06F19/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for string graph assembly of polyploid genomes, the method performed at least one software component executing on at least one processor, comprising:
receiving a string graph generated from sequence reads of at least 0.5 kb in length; identifying unitigs in the string graph and generating a unitig graph; and identifying string bundles in the unitig graph by:
determining a primary contig from each of the string bundles; anddetermining associated contigs that contain structural variations compared to the primary contig. |
| 地址 |
Menlo Park CA US |
