发明名称 |
Process for the synthesis of E1 activating enzyme inhibitors |
摘要 |
<p>The present invention provides processes and synthetic intermediates for the synthesis of 4-substituted (1S, 2S, 4R)-2-hydroxy-4-{7H-pyrrolo[2/3-d]pyrimidin-7 yl}cyclopentyl)methyl sulfamates, which are El activating enzyme inhibitors, and are useful for the treatment of disorders of cell proliferation, particularly cancer, and other disorders associated with El activity.</p> |
申请公布号 |
AU2013204601(B2) |
申请公布日期 |
2015.10.08 |
申请号 |
AU20130204601 |
申请日期 |
2013.04.12 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC |
发明人 |
ELLIOT, ERIC L.;MIZUTANI, HIROTAKE;ARMITAGE, IAN;LANGSTON, STEVEN P.;LANGSTON, MARIANNE;STIRLING, MATTHEW;MCCUBBIN, QUENTIN J.;ZHU, LEI |
分类号 |
C07D487/04;C07C215/44;C07C217/52;C07C219/24 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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