| 主权项 |
1. A method for the prognosis of Symptomatic Multiple Myeloma (MM) and/or to monitor the response and/or the efficacy of a MM therapy comprising:
detecting and/or quantifying at least one marker selected from the group consisting of: C3f peptide or a fragment thereof, 1-arachidonoylglycerophosphocholine, 1-myristoylglycerophosphocholine, 2-palmitoylglycerophosphocholine, 1-pentadecanoylglycerophosphocholine, 1-linoleoylglycerophosphocholine, 1-eicosatrienoylglycerophosphocholine, Creatinine, Glutaroyl carnitine, 2-linoleoylglycerophosphocholine, N-(2-furoyl)glycine, 1-palmitoleoylglycerophosphocholine, Citrate, Carnitine, Sarcosine (N-Methylglycine), 3-hydroxykynurenine, Xanthosine, 1-docosahexaenoylglycerophosphocholine, Testosterone sulfate, 1-palmitoylglycerophosphocholine, Glycerol 3-phosphate (G3P), Acetylcarnitine, N1-methyladenosine, Pro-hydroxy-pro, Urate, 7-alpha-hydroxy-3-oxo-4-cholestenoate (7-Hoca), Cysteine, 2-hydroxybutyrate (AHB), Cortisol, 1-oleoylglycerophosphoethanolamine, Butyrylcarnitine, Pyridoxate, Pseudouridine, 1-stearoylglycerophosphocholine, Palmitoyl sphingomyelin, 1-oleoylglycerophosphocholine, Creatine, 1-docosapentaenoylglycerophosphocholine, Gamma-glutamylphenylalanine, Catechol sulfate, 13-Hydroxyoctadecadienoate (13-HODE), 9-Hydroxyoctadecadienoate (9-HODE), Hexanoylcarnitine, 2-hydroxypalmitate, Indolepropionate, Oleoylcarnitine, Succinate, Tyrosine, Levulinate (4-oxovalerate), Adenosine 5′-monophosphate (AMP), Pyroglutamine, Pregn steroid monosulfate, Alpha-hydroxyisovalerate, Andro steroid monosulfate 2,3-methylhistidine, Lactate, Caprate (10:0), 3-hydroxyisobutyrate, Scyllo-inositol, N-acetyl-beta-alanine, 2-aminobutyrate, Phenyllactate (PLA), Heptanoate (7:0), Beta-hydroxyisovalerate, 3-methoxytyrosine, Deoxycarnitine, 1-palmitoylplasmenylethanolamine, 3-methyl-2-oxobutyrate, 3-phenylpropionate (hydrocinnamate), Propionylcarnitine, Pelargonate (9:0), Tryptophan, 2-stearoylglycerophosphocholine, Pregnenolone sulfate, Phosphate, N-acetylmethionine, Caprylate (8:0), N-formylmethionine, Cyclo(leu-pro), 1-heptadecanoylglycerophosphocholine, Pregnen-diol disulfate, Acetylphosphate, Taurochenodeoxycholate, Arginine, Cholesterol, C-glycosyltryptophan, 4-androsten-3beta.17beta-diol disulfate 1, N-methyl proline, Stearoyl sphingomyelin, Mannose, 21-hydroxypregnenolone disulfate and 1-eicosadienoylglycerophosphocholine in a sample obtained from a subject; optionally comparing the value of the quantified marker to a control value. |
