发明名称 METHOD FOR PREPARING QUINOLONE COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide quinolone compounds useful as anti-infective agents.SOLUTION: This invention relates to quinolone compound of 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt or ester thereof, wherein the compound comprises less than 0.40% of a dimeric impurity of 1-amino-3-(azetidin-3-yloxy)-propan-2-ol-bis(N,N-quinolone carboxylic acid), or a pharmaceutically acceptable salt or ester thereof.
申请公布号 JP2015178515(A) 申请公布日期 2015.10.08
申请号 JP20150101828 申请日期 2015.05.19
申请人 MELINTA THERAPEUTICS INC 发明人 ROGER HANSELMANN;MAXWELL M REEVE;GRAHAM JOHNSON
分类号 C07D401/14;A61K31/4709;A61K47/04;A61K47/12;A61K47/18;A61K47/38;A61P31/04 主分类号 C07D401/14
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