| 发明名称 |
COMPOSITION FOR PREVENTING OR TREATING HEART DISEASE |
| 摘要 |
The present invention relates to a composition for preventing or treating heart disease, and more particularly, to a composition for preventing or treating heart disease, comprising (+)-syringaresinol. Specifically, (+)-syringaresinol as an active ingredient may exhibit excellent effect of preventing or improving heart disease by promoting SIRT1 expression and suppressing death of cardiomyocytes induced by reactive oxygen species. Accordingly, the composition according to the present disclosure may be used to prevent, improve or treat heart diseases including cardiovascular diseases. |
| 申请公布号 |
US2015283110(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
US201314437802 |
申请日期 |
2013.11.29 |
| 申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
Cho Si Young;Seo Dae Bang;Park Chan Woong;Kim Wan Gi;Lee Sang Jun |
| 分类号 |
A61K31/34;A23L1/30 |
主分类号 |
A61K31/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method comprising administrating a composition, which comprises a compound of Chemical Formula 1, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient to a subject in need thereof, wherein the method is for preventing or treating a heart disease: wherein each of R1, R2, R3 and R4 is independently an unbranched or branched C1-C18 alkyl group, C1-C18 alkenyl group, C1-C18 alkynyl group or C3-C6 cyclic alkyl group. |
| 地址 |
Seoul KR |
