| 发明名称 |
DRUG DELIVERY COMPOSITION |
| 摘要 |
A composition for delivery of a drug is disclosed. The composition has a semipermeable coating, particles of a medicament having an effective average particle size of less than or about 2 μm and at least one surface stabilizer adsorbed on the surface of the medicament particles, and a solubilizing agent. |
| 申请公布号 |
US2015283092(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
US201514746035 |
申请日期 |
2015.06.22 |
| 申请人 |
Alkermes Pharma Ireland Limited |
发明人 |
Ruddy Stephen B.;McGurk Simon L.;Patel Rakesh;Bullock John;Kewalramani Raj |
| 分类号 |
A61K9/50;A61K47/20;A61K31/403;A61K31/185;A61K31/436;A61K31/5513 |
主分类号 |
A61K9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A multiparticulate composition comprising a plurality of beads, each bead comprising:
an inert substrate; a solubilizing agent in the form of a surface active agent layer disposed about the inert substrate, a semipermeable coating; and particles of a medicament disposed between the surface-active agent layer and the semipermeable coating, said particles having an effective average particle size of less than or about 2 μm and a surface stabilizer adsorbed on the surface of the medicament particles. |
| 地址 |
Dublin 4 IE |
