发明名称 |
Rodent hepadnavirus cores with reduced carrier-specific antigenicity |
摘要 |
<p>The present disclosure generally relates to hepadnavirus core antigens in which one or more endogenous B cell epitopes have been effectively removed. More specifically, the present disclosure relates to rodent hepadnavirus cores modified to diminish the antibody response to the core so as to enhance the antibody response to heterologous polypeptides included therein.</p> |
申请公布号 |
AU2014228784(A1) |
申请公布日期 |
2015.10.08 |
申请号 |
AU20140228784 |
申请日期 |
2014.03.14 |
申请人 |
VLP BIOTECH, INC. |
发明人 |
MILICH, DAVID R.;WHITACRE, DAVID C. |
分类号 |
A61K9/14;A61K39/00;A61K39/12;A61K39/29;A61K39/38;A61K39/385 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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