| 发明名称 |
ON-DEMAND DRUG RELEASE USING MAGNETO- ELECTRIC NANOPARTICLES |
| 摘要 |
Disclosed herein are methods of delivering drugs to a subject in a controlled release fashion by administering a magneto-electric nanoparticle having ionic bonds to a drug then applying a magnetic field to weaken the ionic bonds and release the drug. |
| 申请公布号 |
US2015283368(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
US201314440274 |
申请日期 |
2013.11.06 |
| 申请人 |
KHIZROEV Sakhrat;NAIR Madhavan P.N.;LIANG Ping;RUNOWICZ Carolyn;GUDURU Rakesh |
发明人 |
Khizroev Sakhrat;Nair Madhavan P.N.;Liang Ping;Runowicz Carolyn;Guduru Rakesh |
| 分类号 |
A61M37/00;A61N2/00;A61K9/50;A61K9/51;A61K31/7072;A61K31/337 |
主分类号 |
A61M37/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method comprising
administering to a subject a plurality of magneto-electric nanoparticles (MENP) having (i) a coating on at least a portion of the MENP surface, said coating one or more of glycerol monooleate, poly L-lysine and polyethylene glycol, and (ii) a drug associated with the MENP through an ionic bond; and applying a magnetic field to the subject to weaken the ionic bond thereby releasing at least a portion of the drug from the MENP. |
| 地址 |
US |
