Tamper-resistant dosage form containing one or more particles

摘要

The invention relates to a tamper-resistant pharmaceutical dosage form comprising one or more particles, wherein each of said one or more particles - comprises a pharmacologically active ingredient and a physiologically acceptable polymer; - has a breaking strength of at least 300 N; - has a weight of at least 2 mg; and - optionally, comprises a film-coating; wherein the total weight of the pharmaceutical dosage form is greater than the total weight of said one or more particles.