发明名称 |
mGluR5ネガティブアロステリックモジュレータとしての置換ヘテロアリールアミド類似体、ならびに、その形成方法および使用方法 |
摘要 |
<p>Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.</p> |
申请公布号 |
JP5792173(B2) |
申请公布日期 |
2015.10.07 |
申请号 |
JP20120529946 |
申请日期 |
2010.09.17 |
申请人 |
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发明人 |
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分类号 |
C07D213/81;A61K31/444;A61K31/506;A61P1/04;A61P25/00;A61P25/04;A61P25/16;A61P25/22;A61P25/30;A61P43/00;C07D401/14;C07D405/14;C07D417/14 |
主分类号 |
C07D213/81 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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