发明名称 がん細胞の化学療法に対する抵抗性を克服するための阻害因子
摘要 The invention provides methods for predicting whether an ovarian cancer patient's tumor will be resistant to chemotherapy. The invention also provides methods for monitoring the effectiveness of treatment, particularly a chemotherapeutic treatment, in a patient treated for ovarian cancer. The invention further provides methods for treating ovarian cancer, by reducing chemotherapeutic drug resistance in said cells. In addition, the invention provides methods of screening compounds to identify tumor cell growth inhibitors in tumor cells resistant to conventional chemotherapeutic treatment regimes.
申请公布号 JP5789591(B2) 申请公布日期 2015.10.07
申请号 JP20120271426 申请日期 2012.12.12
申请人 ザ・ペン・ステート・リサーチ・ファンデーション 发明人 アル−マーラニ、セイマー
分类号 A61K31/7105;A61K31/336;A61K33/24;A61K38/00;A61K48/00;A61P15/00;A61P35/00;A61P43/00;C12N15/113;C12Q1/68 主分类号 A61K31/7105
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