Microfluidic systems

摘要

The systems and methods disclosed herein include a microfluidic system, comprising a pneumatic manifold having a plurality of apertures, and a chip manifold having channels disposed therein for routing pneumatic signals from respective ones of the apertures to a plurality of valves in a microfluidic chip, wherein the channels route the pneumatic signals in accordance with a configuration of the plurality of valves in the microfluidic chip.

主权项

1. A microfluidic system, comprising:
a modular pneumatic manifold having a plurality of apertures that provide a passage of a pneumatic signal there through; a plurality of modular microfluidic chips each having different respective configurations of microfeatures, diaphragm valves, and pressure-actuatable membranes that are actuated by the pneumatic signal disposed in relation to only a single surface of each microfluidic chip; and a respective plurality of separate, modular chip manifolds corresponding to the plurality of microfluidic chips having pneumatic-only channels disposed therein for routing the pneumatic signal from at least some of the apertures of the pneumatic manifold to at least some of the pressure-actuatable membranes on corresponding ones of the microfluidic chips, wherein the channels route the pneumatic signal in accordance with a configuration of the plurality of pressure-actuatable membranes in the microfluidic chip wherein the respective plurality of separate, modular chip manifolds are each disposed in-between and in direct contact with the respective modular microfluidic chips and the modular pneumatic manifold, and the microfluidic system is a reconfigurable system due to the modular microfluidic chips, the separate, modular replaceable chip manifolds, and the separate, modular pneumatic manifold.