发明名称 Therapeutic agent for osteoporosis
摘要 To provide an agent for treating osteoporosis, comprising an acyl thiourea compound represented by the following formula (I) or a salt thereof as an active ingredient:;wherein, R1 represents an optionally substituted C1-6 alkyl group; R2 represents a fluorine atom or a chlorine atom; and R3 represents a hydrogen atom, a fluorine atom, or a chlorine atom.
申请公布号 US9149471(B2) 申请公布日期 2015.10.06
申请号 US201314041222 申请日期 2013.09.30
申请人 NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY;TAIHO PHARMACEUTICAL CO., LTD. 发明人 Miyaura Chisato;Inada Masaki;Fujita Hidenori
分类号 C07D215/00;A61K31/47 主分类号 C07D215/00
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A method for treating osteoporosis, the method comprising administering a pharmaceutical composition comprising an acyl thiourea compound represented by formula (I) or a salt thereof and a pharmaceutically acceptable carrier to a patient in need thereof: wherein, R1 represents an optionally substituted C1-6 alkyl group, wherein a substituent is any one of a hydroxyl group, a C3-10 cycloalkyl group, an optionally substituted C1-6 alkoxy group, an optionally substituted C1-6 alkylamino group, a C1-6 alkanoylamino group, a C1-6 alkylsulfonyl group, an optionally substituted C6-14 aromatic hydrocarbon group, an optionally substituted saturated or unsaturated heterocyclic group, an optionally substituted C1-6 alkylaminocarbonyl group, and an optionally substituted saturated or unsaturated heterocyclic carbonyl group; R2 represents a fluorine atom or a chlorine atom; and R3 represents a hydrogen atom, a fluorine atom, or a chlorine atom.
地址 Fuchu-shi JP