发明名称 |
Therapeutic agent for osteoporosis |
摘要 |
To provide an agent for treating osteoporosis, comprising an acyl thiourea compound represented by the following formula (I) or a salt thereof as an active ingredient:;wherein, R1 represents an optionally substituted C1-6 alkyl group; R2 represents a fluorine atom or a chlorine atom; and R3 represents a hydrogen atom, a fluorine atom, or a chlorine atom. |
申请公布号 |
US9149471(B2) |
申请公布日期 |
2015.10.06 |
申请号 |
US201314041222 |
申请日期 |
2013.09.30 |
申请人 |
NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY;TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
Miyaura Chisato;Inada Masaki;Fujita Hidenori |
分类号 |
C07D215/00;A61K31/47 |
主分类号 |
C07D215/00 |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A method for treating osteoporosis, the method comprising administering a pharmaceutical composition comprising an acyl thiourea compound represented by formula (I) or a salt thereof and a pharmaceutically acceptable carrier to a patient in need thereof: wherein, R1 represents an optionally substituted C1-6 alkyl group, wherein a substituent is any one of a hydroxyl group, a C3-10 cycloalkyl group, an optionally substituted C1-6 alkoxy group, an optionally substituted C1-6 alkylamino group, a C1-6 alkanoylamino group, a C1-6 alkylsulfonyl group, an optionally substituted C6-14 aromatic hydrocarbon group, an optionally substituted saturated or unsaturated heterocyclic group, an optionally substituted C1-6 alkylaminocarbonyl group, and an optionally substituted saturated or unsaturated heterocyclic carbonyl group; R2 represents a fluorine atom or a chlorine atom; and R3 represents a hydrogen atom, a fluorine atom, or a chlorine atom. |
地址 |
Fuchu-shi JP |