Method for producing agglutinating reagent, agglutinating reagent or product produced thereby, and method for measuring analysis object using the same, and test kit and analysis device

摘要

Hemoglobin in a sample solution is quickly and reliably denatured; at the same time, quick and accurate measurement of hemoglobin and a hemoglobin derivative is realized. In a method for measuring hemoglobin and a hemoglobin derivative, and a reagent composition, a measurement kit, an analysis device, and an analysis system used in the method, a sample solution containing a blood component is treated with a nonionic surfactant, an oxidizing agent, and a metal salt to denature hemoglobin in the sample solution to measure the hemoglobin, and thereafter the amount of a hemoglobin derivative in the sample is measured by an immunological method using an antibody specifically binding to a denatured site of the denatured hemoglobin derivative.

主权项

1. A test kit for measuring an analysis object in a test sample by performing particle agglutination control immunoassay, comprising:
an anti-analyte antibody bound to a water suspensible particle, and an agglutinating reagent that comprises a gamma globulin, a ligand having a specific binding site to the anti-analyte antibody, and a linker that has a functional group, wherein the agglutinating reagent is obtained by chemically binding the ligand to the gamma globulin via the linker.