Built-in non-verbal instructional device integratable to applicators

摘要

A built-in non-verbal compact instructional device integratable to an applicator having a microdevice for painlessly perforating skin and optionally an active agent for application to the perforated area. The microdevice can include microneedles, microneedle arrays, microblades, microblade arrays, microknives, microknife arrays, and Functional MicroArrays (FMAs). The active agent can be stored in a first chamber. The microdevice can perforate stratum corneum without significant pain or discomfort to a patient. The active agent is applied to the perforated area. The device verifies compliance with predetermined methods of use, such as a light to indicate application with the recommended amount of force for perforating skin. The applicator can provide enhanced delivery of an active agent, with minimal discomfort, for therapeutic or cosmetic treatment, such as topical treatment for acne, or other skin disorders, wrinkles, blemishes, etc. The applicator is also useful for providing improved systemic or localized delivery of an active agent.

主权项

1. An applicator with at least one built-in non-verbal instructional device comprising:
a hollow body structure having a first end and a second end, and having an exterior surface and an interior surface; said first end of said body structure comprising a microdevice for perforating only the skin's stratum corneum layer for intraepidermal delivery of active agents and at least one built-in non-verbal instructional device to elicit correct behavior, rectify incorrect behavior and improve user compliance by producing instructional signals signifying one or more of the number of applications, the force of each application to validate each application, and the duration of each application; said second end of said body structure comprising at least one opening to allow dispensing of an active agent, that can treat certain diseases, directly to an area of perforated skin from the second end and/or at least one opening to allow dispensing of pigments or inks, to temporarily change the appearance of skin, directly to the area of perforated skin from the second end.