发明名称 |
Piperazine derivatives, methods for preparing same, and uses thereof in the treatment of insulin resistance |
摘要 |
Disclosed herein are compounds and compositions useful in the treatment of pathologies associated with the insulin resistance syndrome (or syndrome X), in particular in the treatment of type 2 diabetes.; |
申请公布号 |
US9150523(B2) |
申请公布日期 |
2015.10.06 |
申请号 |
US201214128381 |
申请日期 |
2012.06.22 |
申请人 |
METABOLYS |
发明人 |
Moinet Gerard;Baverel Gabriel;Nazaret Remi;Ferrier Bernard |
分类号 |
A61K31/496;C07D241/20;C07D213/74;C07D295/088;A61K31/495;A61K31/497;C07D295/096;A61K45/06 |
主分类号 |
A61K31/496 |
代理机构 |
Cantor Colburn LLP |
代理人 |
Cantor Colburn LLP |
主权项 |
1. A compound of formula (I), in which: R1 is —(CH2)4C(O)OH; and; R2 represents:
a phenyl, non-substituted or substituted by one or more substituents, identical or different, chosen from:a C1 to C6 alkoxy group, linear or branched;a halogen atom; ora C1 to C5 alkyl group, linear or branched, substituted by one or more halogen atoms;a monocyclic or polycyclic heteroaryl chosen from |
地址 |
FR |