发明名称 Piperazine derivatives, methods for preparing same, and uses thereof in the treatment of insulin resistance
摘要 Disclosed herein are compounds and compositions useful in the treatment of pathologies associated with the insulin resistance syndrome (or syndrome X), in particular in the treatment of type 2 diabetes.;
申请公布号 US9150523(B2) 申请公布日期 2015.10.06
申请号 US201214128381 申请日期 2012.06.22
申请人 METABOLYS 发明人 Moinet Gerard;Baverel Gabriel;Nazaret Remi;Ferrier Bernard
分类号 A61K31/496;C07D241/20;C07D213/74;C07D295/088;A61K31/495;A61K31/497;C07D295/096;A61K45/06 主分类号 A61K31/496
代理机构 Cantor Colburn LLP 代理人 Cantor Colburn LLP
主权项 1. A compound of formula (I), in which: R1 is —(CH2)4C(O)OH; and; R2 represents: a phenyl, non-substituted or substituted by one or more substituents, identical or different, chosen from:a C1 to C6 alkoxy group, linear or branched;a halogen atom; ora C1 to C5 alkyl group, linear or branched, substituted by one or more halogen atoms;a monocyclic or polycyclic heteroaryl chosen from
地址 FR