| 发明名称 | Isoxazolines as inhibitors of fatty acid amide hydrolase | ||
| 摘要 | The present invention provides isoxazoline FAAH inhibitors of the formula (I):;or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein.;The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient.;The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof. | ||
| 申请公布号 | US9149465(B2) | 申请公布日期 | 2015.10.06 |
| 申请号 | US201012782650 | 申请日期 | 2010.05.18 |
| 申请人 | Infinity Pharmaceuticals, Inc. | 发明人 | Behnke Mark L.;Castro Alfredo C.;Chan Lawrence K.;Evans Catherine A.;Grenier Louis;Grogan Michael J.;Leblanc Yves;Liu Tao;Peluso Stephane;Snyder Daniel A.;Tibbitts Thomas T. |
| 分类号 | C07D261/04;A61K31/5377;A61K31/42;A61K31/4245;A61K31/4439;A61K31/4709;A61K31/501;A61K31/506;C07D413/04;C07D413/12;C07D413/14;C07D471/04 | 主分类号 | C07D261/04 |
| 代理机构 | Jones Day | 代理人 | Jones Day |
| 主权项 | 1. A compound of the formula:or a pharmaceutically acceptable form thereof. | ||
| 地址 | Cambridge MA US | ||